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accession-icon GSE93645
Comparative analysis of gene expression profile of pre-defined niches within demyelinated white matter in rats
  • organism-icon Rattus norvegicus
  • sample-icon 24 Downloadable Samples
  • Technology Badge IconIllumina ratRef-12 v1.0 expression beadchip

Description

Microenviromental niche characterization by comparative transcriptome profiling. The hypothesis tested in the present study was that unique properties of the perivascular niche within remyelinating white matter would create microenvironment that favor the alternative differentiation of oligodendrocyte precursor cells.

Publication Title

Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells.

Sample Metadata Fields

Sex, Specimen part, Time

View Samples
accession-icon GSE49851
Dentate gyrus in epileptic rats
  • organism-icon Rattus norvegicus
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.1 ST Array (ragene11st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Alterations in miRNA levels in the dentate gyrus in epileptic rats.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE49849
Alterations in mRNA levels in the dentate gyrus in epileptic rats
  • organism-icon Rattus norvegicus
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.1 ST Array (ragene11st)

Description

Analysis of the dentate gyrus of amygdala electrical stimulation model of temporal lobe epilepsy. Results provide insight into the molecular mechanism underlying epileptogenesis.

Publication Title

Alterations in miRNA levels in the dentate gyrus in epileptic rats.

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE62252
Expression data from kidney of Grhl1wt and Grhl1 ko mice.
  • organism-icon Mus musculus
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Description

The aim of our study was to investigate the functions of Grhl transcription factor in the kidney.

Publication Title

Consequences of the loss of the Grainyhead-like 1 gene for renal gene expression, regulation of blood pressure and heart rate in a mouse model.

Sample Metadata Fields

Specimen part

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accession-icon GSE57542
Expression data measured by Nanostring and microarray of monocyte-derived dendritic cells from healthy individuals stimulated with LPS, influenza, or IFN-beta, or left unstimulated
  • organism-icon Homo sapiens
  • sample-icon 228 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Common genetic variants modulate pathogen-sensing responses in human dendritic cells.

Sample Metadata Fields

Sex, Age, Race, Subject

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accession-icon GSE36139
SNP and Expression data from the Cancer Cell Line Encyclopedia (CCLE)
  • organism-icon Homo sapiens
  • sample-icon 882 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE36133
Expression data from the Cancer Cell Line Encyclopedia (CCLE)
  • organism-icon Homo sapiens
  • sample-icon 882 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The Cancer Cell Line Encyclopedia (CCLE) project is a collaboration between the Broad Institute, the Novartis Institutes for Biomedical Research and the Genomics Novartis Foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models

Publication Title

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE17312
BI Human Reference Epigenome Mapping Project
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The NIH Roadmap Epigenomics Mapping Consortium aims to produce a public resource of epigenomic maps for stem cells and primary ex vivo tissues selected to represent the normal counterparts of tissues and organ systems frequently involved in human disease.

Publication Title

The NIH Roadmap Epigenomics Mapping Consortium.

Sample Metadata Fields

Sex, Specimen part, Disease, Subject

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accession-icon GSE5258
Connectivity Map dataset (build01)
  • organism-icon Homo sapiens
  • sample-icon 346 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

A reference collection of genome-wide transcriptional expression data for bioactive small molecules.

Publication Title

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE26863
MMRC expression and aCGH reference collection
  • organism-icon Homo sapiens
  • sample-icon 299 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Initial genome sequencing and analysis of multiple myeloma.

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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