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accession-icon GSE9954
Large-scale analysis of the mouse transcriptome
  • organism-icon Mus musculus
  • sample-icon 70 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

We used microarrays to compare gene expression across different murine tissues.

Publication Title

Using ribosomal protein genes as reference: a tale of caution.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE24940
Transcription in adult mouse tissues
  • organism-icon Mus musculus
  • sample-icon 40 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

We used Affymetrix Gene Arrays (1.0 ST) to compare gene expression across different murine tissues.

Publication Title

Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE6933
Unique Molecular Signature of Multipotent Adult Progenitor Cells (Affy)
  • organism-icon Mus musculus, Rattus norvegicus
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302), Affymetrix Rat Expression 230A Array (rae230a)

Description

We compare the transcriptome of embryonic stem cells (ESCs), adult stem cells with apparent greater differentiation potential such as multipotent adult progenitor cells (MAPCs), mesenchymal stem cells (MSCs) and neurospheres (NS). Mouse and rat MAPCs were used in this study and two different array platforms (Affymetrix and NIA) were used for mouse samples.

Publication Title

Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE23984
Effects of TX527, a hypocalcemic vitamin D analog on human activated T lymphocytes
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Hypocalcemic vitamin D analogs are appealing molecules to exploit the immunomodulatory actions of active vitamin D in vivo. The functional modulation of dendritic cells is regarded as the key mechanism underlying their ability to regulate T cell responses. In contrast, the direct actions of vitamin D and structural analogs on T lymphocytes remain less well characterized.

Publication Title

The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.

Sample Metadata Fields

Specimen part, Subject

View Samples
accession-icon GSE6291
Transcriptome Analysis Multipotent Adult Progenitor Cells (Affy)
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

We compare the transcriptome of two different clones of multipotent adult progenitor cells (MAPCs) using Affymetrix arrays.

Publication Title

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE17140
Gene expression profile of myeloma cells treated with IGF-1
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Expression 430A Array (moe430a)

Description

Objective of this study was to find changes in gene expression of mouse multiple myeloma cells upon treatment with IGF-1

Publication Title

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms.

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE48959
Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)
  • organism-icon Homo sapiens
  • sample-icon 48 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE75676
Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients with Fuchs' Dystrophy
  • organism-icon Homo sapiens
  • sample-icon 7 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients With Fuchs' Dystrophy.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE80008
Systemic disease signature of human cutaneous leishmaniasis
  • organism-icon Homo sapiens
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

In addition to the recently published in situ transcriptomics of LCL skin lesions (Novais et al., Khouri et al.), we herein present the first systemic disease signature of localized cutaneous leishmaniasis (LCL), using Affymetrix microarrays (HuGene 1.0) followed by systems biology analysis of the PBMC transciptome of LCL patients (n=18), as compared to healthy controls (n=12).

Publication Title

Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis.

Sample Metadata Fields

Specimen part, Disease stage

View Samples
accession-icon GSE48958
Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC)
  • organism-icon Homo sapiens
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.

Publication Title

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Sample Metadata Fields

Specimen part, Disease

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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