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accession-icon GSE17384
Gene expression data from the LEC rat model with naturally occuring and oxidative stress induced liver tumorigenesis
  • organism-icon Rattus norvegicus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302)

Description

To elucidate the fundamental molecular mechanisms responsible for multistep hepatotumorigenesis, this study investigated genes that were upregulated in a stepwise manner from the nave liver condition through to chronic oxidative stress-induced hepatitis and liver tumor by time-series microarray analysis. The time-dependent gene expression profile should reflect the multistep process of hepatotumorigenesis, and might identify genes that function specifically in hepatotumorigenesis.

Publication Title

IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress.

Sample Metadata Fields

Sex, Age, Specimen part, Disease

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accession-icon GSE75918
DYRK2 regulates cancer stem cell population.
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

We used microarrays to identified new factor that regulates cancer stem cell population in shRNA DYRK2 cells using stable DYRK2 knockdown cells and mammosphere.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE90857
Expression data from Staphylococcus aureus MR23 treated with norgestimate
  • organism-icon Staphylococcus aureus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix S. aureus Genome Array (saureus)

Description

We found that norgestimate effectively inhibits staphylococcal biofilm formation.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE141650
Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1
  • organism-icon Rattus norvegicus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.0 ST Array (ragene10st)

Description

We demonstrated that, four weeks after the pulmonary artery banding (PAB) operation, rats could be divided into two groups: an F+ group in which the fibrotic area occupied more than 6.5% of the whole area of the heart tissues, and an F- group in which the fibrotic area occupied less than 6.5% of this area.

Publication Title

Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1.

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP178159
Clinical study of human mesenchymal stem cells on the treatment of severe liver disease
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

we aimed to explore the potential therapeutic effects of human mesenchymal stem cell on severe liver disease

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP131607
Compare RNA expression of Old Fibroblast to RNA expression of Young Fbroblast
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

Analyze of RNA expression of Old Fibroblast and Young Fibroblast. Compare RNA expression of Old Fibroblast to RNA expression of Young Fbroblast

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP131659
Compare RNA expression of UVA fibroblast to sham fibroblast
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

we analysis of sham fibroblast and UVA fibroblast RNA expression using RNA sequencing and compare RNA expression.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP188485
miR-25 knock out mice kidney RNA sequencing
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

We generate miR-25 KO mice by Cas-9 technology, and run 5 month kidney RNA sequencing.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

View Samples
accession-icon SRP129355
Gene expression change affected by Sirt1 depletion and ionizing radiation in adult neural stem cells
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Adult neural stem cells derived from wild type and Sirt1 conditional knockout mice were treated with or without X-ray, the total RNA extracted from these cells were used for RNA sequencing.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line

View Samples
accession-icon SRP189703
circRNA sequence of HeLa S3 nucleus
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 3000

Description

No description.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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