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accession-icon GSE68454
Systems analysis of uterine and tumor microenvironments
  • organism-icon Mus musculus
  • sample-icon 63 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE68433
Systems analysis of uterine microenvironment 4, 6, 8, 10, 11 or 12 days after fertilization
  • organism-icon Mus musculus
  • sample-icon 33 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo

Publication Title

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE68434
Systems analysis of B16 tumor microenvironment 4 or 14 days after tumor inoculation
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of B16 tumor microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchastrated the immune reponse triggered in presence of tumors

Publication Title

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE68432
Systems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization
  • organism-icon Mus musculus
  • sample-icon 14 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo.

Publication Title

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE40488
Treg cells
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE40443
iTreg cells compared to WT Total Treg
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

iTreg cells from Tbmc mLN mice treated with one week of 1% Oral Ova were compared to Total Treg from WT mice.

Publication Title

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE40441
Comparison of Splenic Nrp1- and Nrp1+ Treg Populations
  • organism-icon Mus musculus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

To compare subpopulations of Treg cells in wild type mice based upon Nrp1 Expression, differentiating nTreg and iTreg

Publication Title

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE6013
Gene expression in asbestos exposed lung cells
  • organism-icon Homo sapiens
  • sample-icon 25 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Asbestos has been shown to cause chromosomal damage and DNA aberrations. The fiber is associated with many different lung diseases such as asbestosis, malignant mesothelioma, and lung cancer, but the disease-related processes are still largely unknown. Our aim was to identify specific gene expression profiles by using Affymetrix arrays, in human cell lines A549, Beas-2B, and MeT5A exposed to asbestos in a time-dependent manner. The hybridization data was analyzed using an algorithm specifically designed for clustering short time series expression data, a canonical correlation analysis (CCA) for identifying correlations between the cell lines, and a Gene Ontology (GO) analysis method for the identification of enriched differentially expressed biological processes.

Publication Title

Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE10799
Gene expression profile of lung tumors
  • organism-icon Homo sapiens
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We have investigated whether the early dissemination of tumor cells into bone marrow is associated with a specific molecular pattern in primary lung cancer

Publication Title

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE12890
Xylose metabolism in recombinant Saccharomyces cerevisiae
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome S98 Array (ygs98)

Description

In the present study transcriptome and proteome of recombinant, xylose-utilising S. cerevisiae grown in aerobic batch cultures on xylose were compared with glucose-grown cells both in glucose repressed and derepressed states. The aim was to study at genome-wide level how signalling and carbon catabolite repression differed in cells grown on either glucose or xylose. The more detailed knowledge about is xylose sensed as a fermentable carbon source, capable of catabolite repression like glucose, or is it rather recognised as a non-fermentable carbon source is important in achieving understanding for further engineering this yeast for more efficient anaerobic fermentation of xylose.

Publication Title

Regulation of xylose metabolism in recombinant Saccharomyces cerevisiae.

Sample Metadata Fields

No sample metadata fields

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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