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accession-icon GSE6843
Male and female embryonic chicken hearts (arnol-affy-chick-445639)
  • organism-icon Gallus gallus
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

The study is relevant to an understanding of the forces that lead to sex differences in the brain and other somatic tissues. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male and female brain differ in their susceptibility to disease.

Publication Title

Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE6844
Male and female embryonic chicken brains (arnol-affy-chick-345142)
  • organism-icon Gallus gallus
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

The study is relevant to an understanding of the forces that lead to sex differences in the brain. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male and female brain differ in their susceptibility to disease.

Publication Title

Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE6856
Male and female embryonic chicken livers (arnol-affy-chick-445002)
  • organism-icon Gallus gallus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

The study is relevant to an understanding of the forces that lead to sex differences in the brain. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male and female brain differ in their susceptibility to disease.

Publication Title

Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE56035
Immune Variation Project (ImmVar)
  • organism-icon Homo sapiens
  • sample-icon 980 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE56033
Immune Variation Project (ImmVar) [CD4]
  • organism-icon Homo sapiens
  • sample-icon 499 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

Gene expression profiling of CD4 T-Cells (CD4+CD62L+) from human peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from healthy individuals from the Boston area.

Publication Title

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE56034
Immune Variation Project (ImmVar) [CD14]
  • organism-icon Homo sapiens
  • sample-icon 481 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

Gene expression profiling of Monocytes (CD14+CD16-) from human peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from healthy individuals from the Boston area.

Publication Title

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE138297
The host response of IBS patients to allogenic and autologous faecal microbiota transfer
  • organism-icon Homo sapiens
  • sample-icon 35 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.1 ST Array (hugene21st)

Description

In this randomised placebo-controlled trial, irritable bowel syndrome (IBS) patients were treated with faecal material from a healthy donor (n=8, allogenic FMT) or with their own faecal microbiota (n=8, autologous FMT). The faecal transplant was administered by whole colonoscopy into the caecum (30 g of stool in 150 ml sterile saline). Two weeks before the FMT (baseline) as well as two and eight weeks after the FMT, the participants underwent a sigmoidoscopy, and biopsies were collected at a standardised location (20-25 cm from the anal verge at the crossing with the arteria iliaca communis) from an uncleansed sigmoid. In patients treated with allogenic FMT, predominantly immune response-related genes sets were induced, with the strongest response two weeks after FMT. In patients treated with autologous FMT, predominantly metabolism-related gene sets were affected.

Publication Title

Allogenic Faecal Microbiota Transfer Induces Immune-Related Gene Sets in the Colon Mucosa of Patients with Irritable Bowel Syndrome.

Sample Metadata Fields

Age, Specimen part, Subject

View Samples
accession-icon GSE24560
Comparative Expression Profiling of E. coli and S. aureus inoculated primary Mammary Gland Cells sampled from Cows with different genetic Predisposition for Somatic Cell Score
  • organism-icon Bos taurus
  • sample-icon 88 Downloadable Samples
  • Technology Badge Icon Affymetrix Bovine Genome Array (bovine)

Description

Establishment of an in vitro system to explore molecular mechanisms of mastitis susceptibility in cattle by comparative expression profiling of Escherichia coli and Staphylococcus aureus inoculated primary cells sampled from cows with different genetic predisposition for somatic cell score

Publication Title

Comparative expression profiling of E. coli and S. aureus inoculated primary mammary gland cells sampled from cows with different genetic predispositions for somatic cell score.

Sample Metadata Fields

Disease, Treatment, Time

View Samples
accession-icon SRP069329
Homo sapiens male germ cell transcriptome
  • organism-icon Homo sapiens
  • sample-icon 34 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

Goal of this study is to identify the transcriptome of human male germ cell subtypes during normal spermatogenesis as a reference for subfertility.

Publication Title

Unraveling transcriptome dynamics in human spermatogenesis.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE14578
Immunopurified mRNA-ribosome complexes expose cell-type specific plasticity during hypoxia in Arabidopsis
  • organism-icon Arabidopsis thaliana
  • sample-icon 94 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis.

Sample Metadata Fields

Age, Specimen part, Treatment

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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