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GSE47632
Arabidopsis thaliana
24 Downloadable Samples
Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)
Description
The root epidermis of Arabidopsis provides a simple and experimentally useful model for studying the molecular basis of cell fate and differentiation. The goal of this study was to define the transcript changes in the root epidermis of mutants associated with root epidermis cell specification, including mutants that lack a visible phenotypic alteration (try, egl3, myb23, and ttg2). Transcript levels were assessed by purifying populations of root epidermal cells using fluorescence-based cell-sorting with the WER::GFP transgene. These microarray results were used to compare the effects of single and double mutants on the gene regulatory network that controls root epidermal cell fate and differentiation in Arabidopsis.
Publication Title
Tissue-specific profiling reveals transcriptome alterations in Arabidopsis mutants lacking morphological phenotypes.
Sample Metadata Fields
Specimen part
View Samples- Homo sapiens
- 363 Downloadable Samples
- Affymetrix Human Genome U219 Array (hgu219)
Description
This study provides an evaluation of changes in gene expression associated with treating human Ishikawa cells with 34 different chemical compounds.
Publication Title
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Sample Metadata Fields
Sex, Cell line
View Samples- Homo sapiens
- 360 Downloadable Samples
- Affymetrix Human Genome U219 Array (hgu219)
Description
This study provides an evaluation of changes in gene expression associated with treating human MCF7 cells with 34 different chemical compounds.
Publication Title
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Sample Metadata Fields
Sex, Cell line
View Samples- Homo sapiens
- 348 Downloadable Samples
- Affymetrix Human Genome U219 Array (hgu219)
Description
This study provides an evaluation of changes in gene expression associated with treating human HEPG2 cells with 34 different chemical compounds.
Publication Title
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Sample Metadata Fields
Sex, Cell line
View Samples- Homo sapiens
- 331 Downloadable Samples
- Affymetrix Human Genome U219 Array (hgu219)
Description
This study provides an evaluation of changes in gene expression associated with treating human HepaRG cells with 34 different chemical compounds.
Publication Title
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Sample Metadata Fields
Sex, Cell line
View Samples- Homo sapiens
- 97 Downloadable Samples
Affymetrix Human Genome U219 Array (hgu219)
Description
This SuperSeries is composed of the SubSeries listed below.
Publication Title
Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
Sample Metadata Fields
Sex, Cell line
View Samples- Arabidopsis thaliana
- 75 Downloadable Samples
- Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)
Description
The root epidermis of Arabidopsis provides a simple and experimentally useful model for studying the molecular basis of cell fate and differentiation. The goal of this study was to define the larger gene regulatory network that governs the differentiation of the root hair and non-hair cell types of the Arabidopsis root epidermis. Transcript levels in the root epidermis of wild-type and mutant lines were assessed by purifying populations of root epidermal cells using fluorescence-based cell-sorting. Further, the role of the plant hormones auxin and ethylene on root epidermis development was assessed by defining transcript levels in the root epidermis of plants grown on media containing IAA or ACC. These microarray results were used to construct a comprehensive gene regulatory network that depicts the transcriptional control of root epidermal cell fate and differentiation in Arabidopsis.
Publication Title
A gene regulatory network for root epidermis cell differentiation in Arabidopsis.
Sample Metadata Fields
Specimen part
View Samples- Arabidopsis thaliana
- 30 Downloadable Samples
- Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)
Description
Gene expression analysis of 7d-old Arabidopsis seedlings exposed to short term (2 h) hypoxia, long term (9 h) hypoxia, and 1 h reoxygenation after long term (9 h) hypoxia to evaluate the regulation of gene expression at the level of translation.
Publication Title
Selective mRNA translation coordinates energetic and metabolic adjustments to cellular oxygen deprivation and reoxygenation in Arabidopsis thaliana.
Sample Metadata Fields
Age
View Samples- Mus musculus
- 12 Downloadable Samples
- Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)
Description
We investigated the effects of diabetes, physical training, and their combination on the gene expression of cardiac muscle. Mice were divided to control (C), training (T), streptozotocin-induced diabetic (D), and diabetic training (DT) groups. Training groups performed 1, 3, or 5 weeks of endurance training on a motor-driven treadmill. Muscle samples from T and DT groups together with respective controls were collected 24 hours after the last training session. Gene expression of cardiac muscles were analyzed using Affymetrix Gene chip MG U74Av2 (Affymetrix , Inc., Santa Clara, CA).
Publication Title
Effects of streptozotocin-induced diabetes and physical training on gene expression of titin-based stretch-sensing complexes in mouse striated muscle.
Sample Metadata Fields
No sample metadata fields
View Samples- Mus musculus
- 12 Downloadable Samples
- Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)
Description
Experiment protocol:
Publication Title
Effects of streptozotocin-induced diabetes and physical training on gene expression of extracellular matrix proteins in mouse skeletal muscle.
Sample Metadata Fields
No sample metadata fields
View Samples