RNA sequencing of CFU-GM derived from CD34+ cells expressing PRR14L shRNA or a scramble control

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SRP162816

Homo sapiens

5 Downloadable Samples

Illumina HiSeq 4000

Submitter Supplied Information

Description

Here we are using RNA-Seq to study the effect of PRR14L knockdown on transcriptome of hematopoietic cells differentiated towards the granulomonocytic lineage. Overall design: RNAseq was performed on individual CFU-GM with shRNA-mediated PRR14L knockdown and scramble control to study the effects of PRR14L knockdown on the transcriptome of hematopoietic cells differentiated towards the granulomonocytic lineage.

PubMed ID

30573780

Publication Title

PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia.

Total Samples

Submitter’s Institution

No associated institution

Authors

Chase A, Pellagatti A, Singh S, Score J, Tapper WJ, Lin F, Hoade Y, Bryant C, Trim N, Yip BH, Zoi K, Rasi C, Forsberg LA, Dumanski JP, Boultwood J, Cross NCP

Source Repository

Sequence Read Archive (SRA)

No rows found