Gata4-dependent differentiation of c-Kit+ derived endothelial cells underlies deceptive cardiomyocyte regeneration in the heart

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SRP131393

Mus musculus

4 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Overall goal: To elucidate the endothelial-specific role of Gata4 signaling in endothelial maturation and vascular maintenance. Purpose of analysis: To generate a transcriptional profile of Gata4-deficient endothelial cells in the adult myocardium under homeostatic conditions. Overall design: Experimental structure: Transcriptional profile generated using RNAseq and differential gene expression analyses of endothelial cells lacking Gata4 isolated from healthy hearts.

PubMed ID

29666070

Publication Title

Gata4-Dependent Differentiation of c-Kit<sup>+</sup>-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart.

Total Samples

Submitter’s Institution

No associated institution

Authors

Maliken BD, Kanisicak O, Karch J, Khalil H, Fu X, Boyer JG, Prasad V, Zheng Y, Molkentin JD

Source Repository

Sequence Read Archive (SRA)

No rows found