In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

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GSE62547

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Human skin-derived precursor cells (hSKP) are a post natal stem cell population isolated from the dermis. These cells acquire hepatic characteristics upon differentiation with hepatogenic factors. Differentiated hSKP show characteristics of hepatocyte precursor cells and respond to hepatotoxic compounds in a comparable way as human hepatocyte cultures.

PubMed ID

25716160

Publication Title

In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

Total Samples

Submitter’s Institution

Vrije Universiteit Brussel

Authors

Rodrigues RM, Branson S, De Boe V, Sachinidis A, Rogiers V, De Kock J, Vanhaecke T

Source Repository

Gene Expression Omnibus (GEO)

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