Effective sorafenib treatment response in a panel of genomically-characterized malignant peripheral nerve sheath tumor orthoxenograft models - refine.bio

GSE60082

Homo sapiens

12 Downloadable Samples

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Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

Background: Malignant peripheral nerve sheath tumors (MPNST) are soft-tissue sarcomas that can arise either sporadically or in association with neurofibromatosis type 1 (NF1). These aggressive malignancies confer poor survival, with no effective therapy available.

PubMed ID

Publication Title

Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine.

Total Samples

12

Submitter’s Institution

Institut de Medicina Predictiva i Personalitzada del Cncer

Authors

Castellsagué J, Gel B, Fernández-Rodríguez J, Llatjós R, Blanco I, Benavente Y, Pérez-Sidelnikova D, García-Del Muro J, Viñals JM, Vidal A, Valdés-Mas R, Terribas E, López-Doriga A, Pujana MA, Capellá G, Puente XS, Serra E, Villanueva A, Lázaro C

Source Repository

Gene Expression Omnibus (GEO)

orthoxenograft passage 1, from NF1-associated MPNST number 1

orthoxenograft

orthoxenograft passage 1, from NF1-associated MPNST number 2

orthoxenograft

primary tumor, from NF1-associated MPNST number 2

primary tumor

orthoxenograft passage 1, from sporadic MPNST number 2

orthoxenograft

orthoxenograft passage 1, from NF1 associated MPNST cell line S462

orthoxenograft

cell line, from NF1 associated MPNST cell line S462

cell line

orthoxenograft passage 1, from sporadic MPNST number 1

orthoxenograft

primary tumor, from sporadic MPNST number 2

primary tumor

primary tumor, from sporadic MPNST number 1

primary tumor

orthoxenograft passage 4, from sporadic MPNST number 2

orthoxenograft

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