Expression data from larvae body wall expressing LaminC transgenes

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GSE49959

Drosophila melanogaster

9 Downloadable Samples

Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Submitter Supplied Information

Description

Expression of mutant lamins in human muscle causes muscular dystrophy. We have generated a drosophila model that expresses mutant lamins, modeled after those that cause disease in humans.

PubMed ID

25996830

Publication Title

Myopathic lamin mutations cause reductive stress and activate the nrf2/keap-1 pathway.

Total Samples

Submitter’s Institution

University of Iowa

Authors

Dialynas G, Shrestha OK, Ponce JM, Zwerger M, Thiemann DA, Young GH, Moore SA, Yu L, Lammerding J, Wallrath LL

Source Repository

Gene Expression Omnibus (GEO)

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