Gene expression profiles MCF-10A cells overexpressing MBD2

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GSE47873

Homo sapiens

6 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Methylated DNA binding protein 2 (MBD2) has been shown to bind specific methylated promoters and suppress transcription. Here we systematically investigate MBD2 suppression by overexpressing MBD2 in MCF-10A cells and generating gene expression profiles of overexpressing cells and normal MCF-10A cells.

PubMed ID

24204564

Publication Title

Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell line.

Total Samples

Submitter’s Institution

McGill University

Authors

Alvarado S, Wyglinski J, Suderman M, Andrews SA, Szyf M

Source Repository

Gene Expression Omnibus (GEO)

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