Exercise and transcriptional analysis in male eNOS Knockout Mice

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GSE1988

Mus musculus

7 Downloadable Samples

Affymetrix Mouse Expression 430A Array (moe430a)

Submitter Supplied Information

Description

There is cardiac dysfunction in male eNOS (-/-) with age and 50% mortality at 21M. It was of interest to investigate the gene expression profile of aged eNOS (-/-) male in comparison to (+/+) in order to explore the genetic markers and molecular mechanisms leading to heart failure. RNA was extracted from the left ventricle from male (-/-) (n=3) and (+/+) (n=4) at the age of 21M.

PubMed ID

15879487

Publication Title

Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.

Total Samples

Submitter’s Institution

New York Medical College

Authors

Ojaimi C, Li W, Kinugawa S, Post H, Csiszar A, Pacher P, Kaley G, Hintze TH

Source Repository

Gene Expression Omnibus (GEO)

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