CDK inhibitor PHA-848125 gene expression profiling on MCF7 cell line

GSE18501

Homo sapiens

3 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

The effects of the CDK inhibitor PHA-848125 (referred to as CDK-125) on the MCF7 human adenocarcinoma mammary cell line were analysed by gene expression profiling.

PubMed ID

20679242

Publication Title

Discovery of drug mode of action and drug repositioning from transcriptional responses.

Total Samples

Submitter’s Institution

Nerviano Medical Sciences srl

Authors

Iorio F, Bosotti R, Scacheri E, Belcastro V, Mithbaokar P, Ferriero R, Murino L, Tagliaferri R, Brunetti-Pierri N, Isacchi A, di Bernardo D

Source Repository

Gene Expression Omnibus (GEO)

GSM461114

MCF7 untreated, rep1

adenocarcinoma mammary cells

mcf7

untreated

GSM461116

MCF7 treated with CDK-125, rep1

adenocarcinoma mammary cells

mcf7

cdk-125

GSM461115

MCF7 untreated, rep2

adenocarcinoma mammary cells

mcf7

untreated

Sample not processed

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GSM461117

MCF7 treated with CDK-125, rep2

adenocarcinoma mammary cells

mcf7

cdk-125